Desloratadine (Clarinex®, Claramax®) is drug which is an antihistamine. It reduces the amount of the histamine chemical, which is being abnormally produced within the body due to exposure to an allergen. Desloratadine (Clarinex®, Claramax®) can be an effective treatment for common allergy symptoms such as runny nose, excessive sneezing and watery eyes. It can also be given to help relieve reoccurring skin reactions such as itching and hives or to treat other medical conditions as determined by a physician.