Seretide Accuhaler (Advair Diskus) is comprised of salmeterol and fluticasone propionate and used to help treat asthmatic patients. Salmeterol targets the muscles within the lungs’ airways, letting them relax and carry more air to facilitate better breathing. Fluticasone propionate is a steroid drug that helps improve breathing, by reducing swelling and helping combat inflammation. Seretide Accuhaler (Advair Diskus) is effective drug therapy for preventing attacks in patients who suffer from asthma.