Olanzapine (Zyprexa®) is a medication considered an antipsychotic, which is atypical for this type of drug. The precise way in which it works on the brain is not known. However, it’s believed to interfere with the actions of specific brain chemicals. Doctors may prescribe Olanzapine (Zyprexa®) to help patients who are suffering from schizophrenia or manic depressive disorders. Olanzapine (Zyprexa®) can be taken by itself and is commonly used in combination with another drug called fluoxetine (Prozac®) to treat clinical depression when other medicines have been unsuccessful.